School of Medicine

Wayne State University School of Medicine

Research Themes

 Members of the CVRI have diverse interests and expertise encompassing:

  • basic science (including computational biology and x-ray crystallography)
  • molecular and cellular biology(regulation of gene expression, mitochondrial bioenergetics and regulation of mitochondrial function, SR protein structure, intracellular stress signaling including structure/function of bioactive lipids, vascular function, inflammation, etc)
  • classic cardiovascular pathophysiology
  • clinical research
  •  patient care
  • community health

By capitalizing on this breadth of knowledge, the member-faculty of the CVRI seek to work together to conduct state-of-the-art translational research that is at the forefront of cardiovascular science.  Current overarching research themes include:

  • myocardial ischemia-reperfusion injury and cardioprotection
  • cerebral ischemia and stroke
  • heart failure
  • hypertension
  • thrombosis, platelet aggregation and coagulation
  • relationships and interactions between cardiovascular diseases and
    • occupational stress
    • diabetes
    • systemic lupus erythematosus
    • sleep apnea
  • cardiovascular health education

Our goal is to obtain novel ‘bench to bedside’ and ‘clinical trial to clinical practice’ insight into each of these important topics by:

  • fostering interaction and collaboration among investigators within each area of strength; and
  • promoting ‘cross-talk’ and interaction among research themes.



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